Identify Rare items of each of the following item types. These can be identified by using a Scroll of Wisdom.

Amulet
Belt
Body Armour
Boots
Gloves
Helmet
Ring
Shield or Quiver
Weapon

Complete each of the following tasks during Blight Encounters.

Build a Blight Tower
Upgrade a Blight Tower
Complete a Blight Encounter

Complete each of the following quests.

The Great White Beast
A Fixture of Fate
The Silver Locket
The Wings of Vastiri
Map to Tsoatha

Defeat each of the following Unique Act Bosses.

Act 1: Merveil, the Twisted
Act 2: Vaal Oversoul
Act 3: Dominus, Ascendant
Act 4: Malachai, The Nightmare
Act 5: Kitava, the Insatiable

Complete each of the following Encounters.

Open a Vaal Vessel in a Vaal Side Area
Gain the Acceleration Shrine buff
Modify an Arcanist’s Strongbox
Defeat a Tormented Thug
Use a Remnant of Corruption on an Essence Monolith

Build each of the following Blight Towers.

Chilling
Empowering
Fireball
Seismic
Shock Nova
Summoning

Complete vendor recipes to receive each of the following items. A vendor recipe is when you trade a specific pattern of items to a vendor, not when you buy items from his/her purchase screen.

Blight Oil
Cartographer’s Chisel
Chaos Orb
Gemcutter’s Prism
Granite Flask
Life Flask
Magic Boots with 10% increased Movement Speed
Orb of Alchemy
Orb of Chance
Vaal Orb

Defeat each of the following Unique Act Bosses.

Act 6: Tsoagoth, The Brine King
Act 7: Arakaali, Spinner of Shadows
Act 8: Lunaris, Eternal Moon and Solaris, Eternal Sun
Act 9: The Depraved Trinity
Act 10: Kitava, the Insatiable

Defeat each of the following Rare Blight Monsters.

Blight Herald
Blight Lurcher
Blighted Ancient Archer
Blighted Arcmage
Blighted Assemblage
Blighted Blood Ape
Blighted Bone Rhoa
Blighted Bonestalker
Blighted Bramble Cobra
Blighted Brine
Blighted Bullock
Blighted Burned Hellion
Blighted Cannibal
Blighted Carnage Ape
Blighted Chieftain
Blighted Cinder Elemental
Blighted Colossal
Blighted Cultist
Blighted Dead
Blighted Deadeye
Blighted Devil
Blighted Elite
Blighted Evangelist
Blighted Experimenter
Blighted Fiend
Blighted Fire-eater
Blighted Fire-raiser
Blighted Fowl
Blighted Frozen Titan
Blighted Gladiator
Blighted Goliath
Blighted Great Rhoa
Blighted Guardian
Blighted Hellion
Blighted Highwayman
Blighted Hound
Blighted Icy Manifestation
Blighted Impaler
Blighted Incinerator
Blighted Initiate
Blighted Lanternbearer
Blighted Larva
Blighted Leaping Spider
Blighted Mage
Blighted Miner
Blighted Murk Runner
Blighted Necromancer
Blighted Outcast
Blighted Pitbull
Blighted Punisher
Blighted Rattler
Blighted Regurgitator
Blighted Relic
Blighted Rhoa Scavenger
Blighted Rumbler
Blighted Scout
Blighted Serpent
Blighted Shaman
Blighted Sister
Blighted Sniper
Blighted Spawn
Blighted Spider Crab
Blighted Spine Construct
Blighted Spray Crab
Blighted Stalker
Blighted Stone Crab
Blighted Tarantula
Blighted Thug
Blighted Thundercaller
Blighted Tidal Crab
Blighted Undying
Blighted Virulent Spider
Blighted Volatile Fire
Blighted Ward
Blighted Wolf Alpha
Blighted Zealot
Blighted Zombie Rhoa

Defeat The Elder and each of his Guardians.

The Enslaver
The Eradicator
The Constrictor
The Purifier
The Elder

Defeat each of the following Rogue Exiles.

Ailentia Rac
Antalie Napora
Armios Bell
Ash Lessard
Augustina Solaria
Aurelio Voidsinger
Baracus Phraxisanct
Bolt Brownfur
Damoi Tui
Dena Lorenni
Eoin Greyfur
Igna Phoenix
Ion Darkshroud
Jonah Unchained
Kirmes Olli
Lael Furia
Magnus Stonethorn
Minara Anemina
Ohne Trix
Orra Greengate
Oyra Ona
Thena Moga
Thom Imperial
Tinevin Highdove
Torr Olgosso
Ultima Thule
Ulysses Morvant
Vanth Agiel
Vickas Giantbone
Wilorin Demontamer
Xandro Blooddrinker
Zacharie Desmarais

Use the Crafting Bench to craft a modifier on the following item slots.

Amulet
Belt
Body Armour
Boots
Gloves
Helmet
Ring
Shield or Quiver
Weapon

Turn in Divination Cards which specifically grant each of the following reward types.

Bow
Corrupted Item
Currency
Divination Card
Essence
Gem
Map
Ring

Complete each of the following Encounters.

Defeat Shavronne the Sickening in the Cells Map while she has full Energy Shield.
Defeat Pagan Bishop of Agony in the Cursed Crypt Map while he is affected by at least 2 Curses.
Defeat Rek’tar, the Breaker in the Glacier Map after he has become exhausted at least 3 times.
Defeat Barthol, the Corruptor in the Haunted Mansion Map while affected by a Heretical Flare.

Complete Blight Encounters while each of the following conditions are true.

With no Towers built
While the Ichor Pump has 1 Durability remaining
While the Ichor Pump is at full Durability

Anoint the following items by using Blight Oils.

Amulet
Ring
Blighted Map
Blight Unique Item

Complete 10 of the following 15 Map Tiers while they have the Twinned modifier. Maps are completed by killing their Unique Bosses.

Tier 1
Tier 2
Tier 3
Tier 4
Tier 5
Tier 6
Tier 7
Tier 8
Tier 9
Tier 10
Tier 11
Tier 12
Tier 13
Tier 14
Tier 15

Open the following Blight chests the specified number of times.

Blight Cyst (9/650)
Blight Pustule (1/150)
Blight Sack (0/150)

Complete Rare Maps in 10 of the following 16 tiers while they are unidentified. These Maps are completed by killing their Unique Bosses.

Tier 1
Tier 2
Tier 3
Tier 4
Tier 5
Tier 6
Tier 7
Tier 8
Tier 9
Tier 10
Tier 11
Tier 12
Tier 13
Tier 14
Tier 15
Tier 16

Use the Ascendancy Device in all 4 Labyrinths.

The Labyrinth
The Cruel Labyrinth
The Merciless Labyrinth
The Eternal Labyrinth

Defeat each of the following Unique Blight Monsters.

Arduk, Spreader of Rot
Axehorn, Earth Flattener
Banisher of the Cleansed
Beacon of Inevitability
Clobberclaw
Eden, Blightspeaker
Ephrexis, Blight Strider
Gangrel, the Mangled
Ghroth, Sporebreath Corruptor
Hazarat, the Propagator
Jodin Dusk, Infected Advocate
Knucklegnaw
Lathaniel, the Mindless
Mishne, Stipecrawler
Orolath, Slug Crusher
Rattleback, Hollow Matriarch
Rosaria, Spore Siren
Scree, the Infected
Sharnath
Sketh, Spore Amalgamation
Sporeplume
Stenly, the Rot-Headed
Vilislatha
Ystral, Winter Stalker

Complete each of the following Encounters.

Defeat Harbingers (0/150)
Defeat Warband Generals (0/50)
Open Breaches (0/150)
Open Maps with Fortune Favours the Brave (0/30)

Complete one of the following Synthesis Unique Maps.

Cortex
Altered Distant Memory
Augmented Distant Memory
Twisted Distant Memory
Rewritten Distant Memory

Build each of the following Blight Towers.

Arc Tower
Flamethrower Tower
Freezebolt Tower
Glacial Cage Tower
Imbuing Tower
Lightning Storm Tower
Meteor Tower
Scout Tower
Sentinel Tower
Smothering Tower
Stone Gaze Tower
Temporal Tower

Obtain 19 of the following 23 reward types from Blight Chests.

Abyss
Armours
Bestiary
Blight
Breach
Currency
Divination Cards
Essences
Fossils
Fragments
Gems
Generic
Harbinger
Labyrinth
Legion
Maps
Perandus
Prophecies
Scarabs
Talismans
Trinkets
Uniques
Weapons

Complete each of the following Legion encounters.

Complete a Legion Encounter in the Azurite Mine.
Complete a Legion Encounter in the Temple of Atzoatl.
Obtain a Legion Reward from a Betrayal Safehouse.
Use a Legion Scarab in the Map Device with a Map.
Complete a Map affected by a Legion Sextant modifier.
Complete the Domain of Timeless Conflict.

Use each of the following Blight Oils to modify items.

Clear Oil
Sepia Oil
Amber Oil
Verdant Oil
Teal Oil
Azure Oil
Violet Oil
Crimson Oil
Black Oil
Opalescent Oil
Silver Oil
Golden Oil

Spend Blight Resources on each of the following Tower Types.

Cold (0/200,000)
Lightning (0/200,000)
Fire (0/200,000)
Physical (0/200,000)
Minion (0/200,000)
Buff (0/200,000)

Attain character level 90. This challenge still counts even if your character dies afterwards.

Complete each of the following Encounters.

Defeat Bazur in the Tower Map without being hit by any of Liantra’s skills after having killed at least 8 Tomes of Thunder.
Defeat Nightmare Manifest in the Malformation Map while 7 Eye Hatcheries are alive.
Defeat Jaesyn, Kruug, the Frayed, Balah, Duke and Maker of Mires in the Hallowed Ground Map within 10 seconds of one another.
Defeat Kitava, The Destroyer in the Lava Lake Map without killing any Champions or Shamans of the Feast.

Complete Blight Encounters that have at least the following number of lanes while receiving a reward from all spawned lanes. This cannot be completed in a Blighted Map.

Two
Three
Four
Five
Six
Seven
Eight

Complete Blighted Maps that are affected by each of the following modifiers with at least the specified magnitudes.

10% reduced Monster Movement Speed
Towers deal 20% more Damage
20% reduced Cost of Building and Upgrading Towers
3 Blight Chests are Lucky
15% increased Experience gain
35% chance for Blight Chests to drop an additional Reward

Complete each of the following Encounters.

Kill 1000 Monsters in a single Rampage kill streak
Defeat a Possessed Beyond Boss
Complete The Beachhead
Defeat the Pale Council

Complete 525 Atlas Missions.

Complete any 15 of the following 19 Unique Maps on your Atlas. A Map is completed by killing its Unique Boss or Bosses if it has any. Maps without Unique Bosses are completed by opening specific Unique Chests.

Acton’s Nightmare
Caer Blaidd, Wolfpack’s Den
Death and Taxes
Doryani’s Machinarium
Hall of Grandmasters
Hallowed Ground
Maelström of Chaos
Mao Kun
Oba’s Cursed Trove
Olmec’s Sanctum
Perandus Manor
Pillars of Arun
Poorjoy’s Asylum
The Coward’s Trial
The Putrid Cloister
The Twilight Temple
The Vinktar Square
Vaults of Atziri
Whakawairua Tuahu

Complete each of the following Encounters.

Defeat Chayula, Who Dreamt outside of its Domain
Defeat Amanamu, Liege of the Lightless while at least 2 Stygian Hearts are active
Defeat a Bestiary Boss
Defeat The Vaal Omnitect while you are affected by a Tempest and Lightning Exposure

Complete Rare Blighted Maps in each of the following tiers.

Tier 1
Tier 2
Tier 3
Tier 4
Tier 5
Tier 6
Tier 7
Tier 8
Tier 9
Tier 10
Tier 11
Tier 12
Tier 13
Tier 14
Tier 15

Complete each of the following deadly encounters.

Mastermind at an area level of 83
The Shaper
Aul, the Crystal King
Atziri in the Alluring Abyss

Complete the entire questline given by Zana.

Complete any 4 of these encounters the specified number of times.

Level 100
Defeat Uber Elder (0/40)
Defeat Shaper Guardians or The Shaper (0/125)
Defeat Argus in the Endgame Labyrinth (0/100)
Complete Blighted Maps (0/100)
Spend Sulphite in the Azurite Mine (0/650,000)